General Information

  • ID:  hor003106
  • Uniprot ID:  A0A0L0CNJ2
  • Protein name:  sNPF-3
  • Gene name:  NA
  • Organism:  Lucilia cuprina (Green bottle fly) (Australian sheep blowfly)
  • Family:  NPY family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Lucilia (genus), Luciliinae (subfamily), Calliphoridae (family), Oestroidea (superfamily), Calyptratae, Schizophora, Cyclorrhapha, Eremoneura, Muscomorpha (infraorder), Brachycera (suborder), Diptera (order), Endopterygota (cohort), Neoptera (infraclass), Pterygota (subclass), Dicondylia, Insecta (class), Hexapoda (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  KPQRLRF
  • Length:  7
  • Propeptide:  MHFQSQLIYKLTLGTFLMLWAQTSAEVLRDEASLNNLYNNLLQREYAGPVVFPNHQVERKAQRSPSLRLRFGRRSDPDLLSQTPEKRWFGEVNQKPIRSPSLRLRFGRRSDPSMPMHSPYDILMNGQQMPENNDDYNEIYDAYYNRVVRKPQRLRFGRSLPFQTMNAVNENDLLESGDDNNDMTLPNSEDEFYNTLIHSQKLRNLLMSLNKYGAGQDNEGMDTAEEDMDEFERAIRKPGPLRLRWGRSTGGRSSMLDKEIKGKDELEQKNKVSEVVNDVVDKSVNQQNKD
  • Signal peptide:  MHFQSQLIYKLTLGTFLMLWAQTSA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  AF-A0A0L0CNJ2-F1(AlphaFold_DB_ID)
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor003106_AF2.pdbhor003106_ESM.pdb

Physical Information

Mass: 105134 Formula: C43H73N15O9
Absent amino acids: ACDEGHIMNSTVWY Common amino acids: R
pI: 12.52 Basic residues: 3
Polar residues: 0 Hydrophobic residues: 2
Hydrophobicity: -162.86 Boman Index: -3303
Half-Life: 1.3 hour Half-Life Yeast: 3 min
Half-Life E.Coli: 2 min Aliphatic Index 55.71
Instability Index: 5282.86 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  23280433
  • Title:  Neuropeptidomics of the Australian Sheep Blowfly Lucilia Cuprina (Wiedemann) and Related Diptera